14 Department of Research, Nemours/Alfred I.duPont Hospital for Children, Wilmington, Delaware Department of Pediatrics, Shimane University, Shimane, Japan Department of Pediatrics, Graduate School of Medicine, Gifu University, Gifu, Japan Department of Pediatrics, Thomas Jefferson University, Philadelphia, Pennsylvania. 13 Department of Pediatrics, Graduate School of Medicine, Gifu University, Gifu, Japan.Louis, Missouri Department of Biochemistry and Molecular Biology, Saint Louis University, St. 12 Department of Pediatrics, Saint Louis University, St.11 Department of Pediatrics, Shimane University, Shimane, Japan.10 Vietnam National Children's Hospital, Department of Medical Genetics, Metabolism and Endocrinology, Hanoi, Vietnam.9 Instituto Nacional de Ciência e Tecnologia de Genética Médica Populacional, Porto Alegre, Brazil Medical Genetics Service, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil Postgraduate Program in Medicine, Medical Sciences, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil Department of Genetics, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.8 Instituto Nacional de Ciência e Tecnologia de Genética Médica Populacional, Porto Alegre, Brazil Medical Genetics Service, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil Postgraduate Program in Medicine, Medical Sciences, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.7 Haemotherapy Service, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil Department of Internal Medicine, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.duPont Hospital for Children, Wilmington, Delaware. 6 Department of Research, Nemours/Alfred I.duPont Hospital for Children, Wilmington, Delaware Department of Biological Sciences, University of Delaware, Newark, Delaware. 5 Department of Research, Nemours/Alfred I.4 Department of Pediatrics, Osaka City University Graduate School of Medicine, Osaka, Japan.3 Medical Education Development Center, Gifu University, Gifu, Japan.2 Department of Cell Transplantation and Regenerative Medicine, Tokai University School of Medicine, Isehara, Japan.duPont Hospital for Children, Wilmington, Delaware Department of Biological Sciences, University of Delaware, Newark, Delaware Instituto Nacional de Ciência e Tecnologia de Genética Médica Populacional, Porto Alegre, Brazil. 1 Department of Research, Nemours/Alfred I.

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